Sonic diagnosis of bone fracture healing--a preliminary study.
نویسندگان
چکیده
The definition of bone fracture healing onset, progress and extent is a difficult clinical diagnosis. Available criteria of manual stability, X-ray appearance, symptomatic pain and passage of time are indeed valuable, but subjective in nature. This study explores the transmission and comparative measurement of stress wave disturbances across a fracture site as a technique of quantifying the union state. Results from laboratory animal experimentation and subsequent clinical usage indicate a potentially valuable method has been developed.
منابع مشابه
Potential Role of Local Estrogen in Enhancement of Fracture Healing: Preclinical Study in Rabbits
Background: Effects of estrogen on bone metabolism and its protective role on prevention of osteoporosis are well documented. However, the efficacy of estrogen treatment on bone healing is not well investigated. The drug can be delivered both systemically or locally to the bone with differences in concentrations and side effects. The aim of this study was to investigate the effect of lo...
متن کاملHealing the Bone
Healing of the bone is different with the other part of the body. Fracture healing is actually a bone regeneration with no scar tissues, where as in wound healing, injured tissue is replaced by connective tissue which became a scar, Traditionally fracture healing is divided in to 4 stages: 1) Stage of inflammation; 2) Stage of soft callus; 3) Stage of hard callus and 4) Stage of remodeling. In...
متن کاملIs Sonic Hedgehog Involved in Human Fracture Healing? - A Prospective Study on Local and Systemic Concentrations of SHH
INTRODUCTION Sonic Hedgehog (SHH) is a new signalling pathway in bone repair. Evidence exist that SHH pathway plays a significant role in vasculogenesis and limb development during embryogenesis. Some in vitro and animal studies has already proven its potential for bone regeneration. However, no data on the role of SHH in the human fracture healing have been published so far. METHODS Seventy-...
متن کاملExpression and Role of Sonic Hedgehog in the Process of Fracture Healing with Aging.
Aging is one of the risk factors for delayed fracture healing. Sonic hedgehog (SHH) protein, an inducer of embryonic development, has been demonstrated to be activated in osteoblasts at the dynamic remodeling site of a bone fracture. Herein, we compared and examined the distribution patterns of SHH and the functional effect of SHH signaling on osteogenesis and osteoclastogenesis between young (...
متن کاملHistological Evaluation of the Effect of Sildenafil and Pentoxifylline on Mandibular Fracture Healing in Rats
Background and Aim: Despite the advances in maxillofacial surgery, impaired bone healing remains a concern for surgical teams. Effects of sildenafil and pentoxifylline on healing of bone fractures have not been well investigated. This study aimed to assess the effects of sildenafil and pentoxifylline phosphodiesterase inhibitors on healing of mandibular fractures in rats. Materials and Methods...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of biomechanics
دوره 9 11 شماره
صفحات -
تاریخ انتشار 1976